Yuh Min Chook, a leader
in nuclear transport: "The newly
discovered 3 dimensional
structure of Crm1 (Nature, 2009)
can facilitate the discovery of selective modulators of nuclear
transport to provide new therapies for Cancer."
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Welcome to Karyopharm
Karyopharm Therapeutics is a biopharmaceutical company focusing on the development of novel drugs for the treatment of cancer, inflammation and diseases related to cell proliferation.
Karyopharm Therapeutics is developing small molecule drugs that will modulate
the activity of critical pathways in cancer, inflammation, and cell
proliferation (e.g. FOXO, NFкB, P53, pRB) by targeting the nuclear pore
complex machinery, which controls the import and export of proteins between
the nucleus and cytoplasm.
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Our Mission . . .
is to discover and develop new therapies to prevent, treat and cure diseases
such as cancer, and inflammation, and viral infection.
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