Lori Macomber

Executive Vice President, Chief Financial Officer and Treasurer

Lori Macomber joined Karyopharm in January 2025 and is responsible for leading and directing the financial activities of the Company.  Ms. Macomber is a seasoned global finance executive with over 30 years of experience in the biotechnology and pharmaceuticals sector. She has a proven track record in financial management for companies ranging from start-up to Fortune 500 and has also successfully supported various collaboration partnerships, business development activities and licensing deals.

Previously, she served as the Chief Financial Officer at Legend Biotech.  Prior to Legend Biotech, she held various financial positions of increasing responsibility in external and internal auditing, financial planning and analysis, and controllership at Eli Lilly and Company, Pfizer (formerly Pharmacia), Schering Plough, and Johnson & Johnson.

Ms. Macomber holds a Mini-MBA in BioPharma Innovation from Rutgers University and a Bachelor of Science in Accounting from Pennsylvania State University. She is a Certified Public Accountant and a Six Sigma Green Belt.